Arbutin is White needle crystal or powder, while it's Molecular Formula is C12H16O7. White needle crystal or powder veterinary drug

What is the CAS number for Arbutin?

The CAS number of Arbutin is 497-76-7.

What is Arbutin (497-76-7) used for?

Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.InChI:InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9+,10+,11-,12-/m1/s1

Arbutin is White needle crystal or powder, while it's Molecular Formula is C12H16O7. White needle crystal or powder veterinary drug

What is the CAS number for Arbutin?

The CAS number of Arbutin is 497-76-7.

What is Arbutin (497-76-7) used for?

Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.InChI:InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9+,10+,11-,12-/m1/s1

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497-76-7

Product Name：Beta Arbutin
Molecular Formula：C₁₂H₁₆O₇
Purity：99%
Molecular Weight：272.255

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Product Details

pd_meltingpoint:195-198 °C

Appearance:White needle crystal or powder

Buy Quality Beta Arbutin 497-76-7 In Stock with Immediately Delivery

Molecular Formula:C12H16O7
Molecular Weight:272.255
Appearance/Colour:White needle crystal or powder
Vapor Pressure:1.9E-13mmHg at 25°C
Melting Point:195-198 °C
Refractive Index:-65.5 ° (C=4, H2O)
Boiling Point:561.583 °C at 760 mmHg
PKA:10.10±0.15(Predicted)
Flash Point:293.435 °C
PSA：119.61000
Density:1.556 g/cm³
LogP:-1.42910

Arbutin(Cas 497-76-7) Usage

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