70356-09-1
- Product Name:Avobenzone
- Molecular Formula:C20H22O3
- Purity:99%
- Molecular Weight:310.393
Product Details
pd_meltingpoint:81-84 °C
Appearance:white powder
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What is the Avobenzone ?
Avobenzone is white powder, while it's Molecular Formula is C20H22O3 . Avobenzone provides strong absorption through a large portion of the UVA spectrum including the majority of the UVA I range with peak absorption at 360 nm. Photostability refers to the ability of a molecule to remain intact with irradiation. It is potentially a problem with all UV filters, but particularly with the use of avobenzone. This effect may degrade other sunscreens in a formulation including octyl methoxycinnamate. Octocrylene and some of the newer sunscreens including BEMT stabilized avobenzone. Non-UV filters such as diethylhexyl 2,6 naphthalate may also be used. These molecules function as triplet–triplet quenchers. Overall formulation with avobenzone is therefore particularly critical.
What is the CAS number for Avobenzone ?
The CAS number of Avobenzone is 70356-09-1.
More information of Avobenzone 70356-09-1 are:
Synonyms |
1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione;1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propan-1,3-dione;4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane;4-Methoxy-4'-tert-butyldibenzoylmethane;4-tert-Butyl-4'-methoxydibenzoylmethane;1,3-Propanedione,1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-;Butylmethoxydibenzoylmethane;Escalol 517;Eusolex 9020;NeoHeliopan 357;Parsol 1789;Parsol A;Parsol RTM 1789;Photoplex; |
CAS Number |
70356-09-1 |
Molecular Formula |
C20H22O3 |
Molecular Weight |
310.393 |
Density |
1.079 g/cm3 |
Melting Point |
81-84 °C |
Boiling Point |
463.6 °C at 760 mmHg |
Flash Point |
203.1 °C |
HS CODE |
29145000 |
PSA |
43.37000 |
LogP |
4.44840 |
Pka |
9.74±0.13(Predicted) |
What is Avobenzone (70356-09-1) used for?
Avobenzone is a full-spectrum ultraviolet A (UVA) blocker. It inhibits UVA-induced increases in melanin levels and tyrosinase activity in B16/F10 melanoma cells (IC30s = 21.94 and 24.25 μM, respectively). Avobenzone (30 μM) also inhibits UVA-induced production of reactive oxygen species (ROS) and 8-hydroxy-2''-deoxyguanosine (8-OH-dG; ), as well as inhibits UVA-induced depletion of glutathione (GSH; ), in B16/F10 cells. It increases nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and upregulates the antioxidant response element (ARE) in UVA-irradiated B16/F10 cells when used at at a concentration of 30 μM. Formulations containing avobenzone have been used as a sun protectant in sunscreen products.
InChI:InChI=1/C20H22O3/c1-2-3-10-15-23-20(18(21)16-11-6-4-7-12-16)19(22)17-13-8-5-9-14-17/h4-9,11-14,20H,2-3,10,15H2,1H3
Articles related to Avobenzone:
Article |
Source |
Photodegradation of avobenzone: Stabilization effect of antioxidants |
Afonso,Horita,Sousa E Silva,Almeida,Amaral,Lob?o,Costa,Miranda, Margarida S.,Esteves Da Silva, Joaquim C.G.,Sousa Lobo , p. 36 - 40 (2014) |
High-yield production process for 1,3-diphenyl propanedione compound |
- Paragraph 0085-0114, (2019/02/19) |
How to get the best price on Avobenzone?
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