4759-48-2
- Product Name：Isotretinoin
- Molecular Formula：C20H28O2
- Purity：99%
- Molecular Weight：300.441
Product Details
pd_meltingpoint:172-175 °C(lit.)
Appearance:yellowish crystalline powder
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What is the Isotretinoin ?
Isotretinoin is yellowish crystalline powder, while it's Molecular Formula is C20H28O2. isotretinoin is a retinoid derivative with improved bioavailability and percutaneous absorption for acne treatment products. Presently being studied in conjuction with the treatment of photoaged skin.
What is the CAS number for Isotretinoin ?
The CAS number of Isotretinoin is 4759-48-2.
More information of Isotretinoin 4759-48-2 are:
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Synonyms |
Isotretinoin [USAN:BAN:INN];(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoate;Retinoic acid, (13cis)-;13-cis-Retinoic acid;Isotretinoin Retinoic acid;Prestwick_642;Neovitamin A acid;Claravis;Teriosal;Roaccutan;Isotretion;Isotretinoin?;Isotretinoine [INN-French];isoretinoin;4-09-00-02388 (Beilstein Handbook Reference); |
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CAS Number |
4759-48-2 |
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Molecular Formula |
C20H28O2 |
|
Molecular Weight |
300.441 |
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Density |
1.011 g/cm3 |
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Melting Point |
172-175 °C(lit.) |
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Boiling Point |
462.8 °C at 760 mmHg |
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Flash Point |
350.6 °C |
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HS CODE |
29362100 |
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PSA |
37.30000 |
|
LogP |
5.60260 |
|
Pka |
4.76±0.33(Predicted) |
What is Isotretinoin (4759-48-2) used for?
Isotretinoin is the 9-cis isomer of retinoic acid, a close relative of retinol, or vitamin A. It was originally developed to treat cystic acne, and today this is still its primary use despite several more modern applications of the drug, including a treatment for pancreatic and brain cancers. First shown to be an effective treatment for acne in 1982, its development stemmed from advances in knowledge of the effects of vitamin A to reduce or eliminate sebum production. Since that time, however, several instances of deleterious effects became well known, most notably birth defects arising from the use of isotretinoin.
InChI:InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/p-1/b9-6+,12-11+,15-8+,16-14-
Articles related to Isotretinoin:
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Article |
Source |
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Catalytic synthesis of 9-cis-retinoids: Mechanistic insights |
Kahremany, Shirin,Kubas, Adam,Tochtrop, Gregory P.,Palczewski, Krzysztof supporting information, p. 10581 - 10595 (2019/07/22) |
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STEREOSPECIFIC SYNTHESIS PROCESS FOR TRETINOIN COMPOUNDS |
- Paragraph 0043; 0044, (2014/04/03) |
How to get the best price on Isotretinoin?
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